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BIND Reader >> SCREENERThe BIND® SCREENER is label-free, plate-based reader designed for ultra-high throughput environments and provides quantitative measurements of a variety of cellular and biochemical interactions. The SCREENER is a small footprint, bench-top instrument capable of reading 96-, 384-, 384LV- and 1536-well Biosensor plates. It is easily integrated within a variety of automation platforms. Throughput can be maximized using the TURBO read mode option which allows a 1536-well plate to be read in as little as 45 seconds.>> Download PDF |
BIND Reader >> PROFILERThe BIND® PROFILER is a small footprint, high throughput plate reader for the label-free measurement of a variety of biomolecular interactions. The PROFILER was designed with flexibility in mind to enable researchers to seamlessly move from target discovery and assay development to full screening and compound profiling. It is ideal for GPCR and ion channel assays, including endogenous receptor systems and assessment of primary cells, as well as for biochemical assays such as protein:protein binding, fragment-based and small molecule screening assays.>> Download PDF |
BIND Reader >> EXPLORERThe BIND® EXPLORER is a small footprint, plate-based reader for quantitative, label-free measurements of a variety of biomolecular interactions. BIND® enables maximum application flexibility ranging from biochemical binding assays to complex cellular assays including primary cell, GPCR, ion channel and cell adhesion assays. The EXPLORER’s ability to collect kinetic data provides an additional layer of information that is useful in determining binding characteristics, mechanisms of action or even pathway usage upon GPCR activation.>> Download PDF |
BIND Reader >> CartridgeThe BIND® Cartridge Reader is a unique and cost-effective solution for lower throughput, label-free assays with the sophistication of higher-end instrumentation. It is a true bench top instrument with approximately the same footprint as a microcentrifuge. This reader was engineered from the ground up with application flexibility in mind and can be used for both biochemical and cell-based assays. Assays are performed in 16- well BIND® Biosensor Cartridges, an ideal format for assay development or for profiling individual compounds. Because the Cartridge Reader uses identical technology as SRU’s plate-based BIND® Readers, assays developed in cartridge format can easily be migrated to the higher throughput EXPLORER, PROFILER or SCREENER BIND Readers.>> Download PDF |
BIND Biosensors >> Biochemical ApplicationsBIND® from SRU Biosystems is a label-free, universal assay platform for the detection of biomolecular interactions. The platform is comprised of a BIND® Reader and associated BIND® Biosensor plates. An independent, optical biosensor is incorporated into the bottom of each well of the Biosensor plates. The biosensors provide very sensitive measurements of changes in mass or binding in proximity to the biosensor surface. A range of biosensor surface chemistries has been developed for optimum results for a variety of biochemical assays including protein-protein binding, small molecule binding, protein-nucleic acid binding and enzyme assays.>> Download PDF |
BIND Biosensors >> Cellular ApplicationsBIND® from SRU Biosystems is a label-free, universal assay platform for a wide range of cell-based applications. The platform is comprised of a BIND® Reader and associated BIND® Biosensor plates. An independent, optical biosensor is incorporated into the bottom of each well of the Biosensor plates. BIND Biosensors are available with a number of optimized surfaces for measuring biological responses of both adherent and suspension cell types including primary cells. Robust, reproducible responses are produced for both recombinant and endogenous targets requiring as few as 1,000 cells per well in 1536- well format. BIND assays are non-destructive, live cell assays that are more physiologically relevant because they are label-free.>> Download PDF |
BIND Applications - Cytotoxicity AssaysCompound Cytotoxicity Screening & Cardiomyocyte Toxicity Assay>> Download PDF |
Cell-based, Label-free Receptor Assays One Technology - Any ReceptorGPCR Assay Solutions and Ion Channel Assays.>> Download PDF |
BIND® Cartridge ReaderThe COMPLETE label-free solution for under $50K.... ....with the ULTIMATE in application flexibility>> Download PDF |
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