Applications
BIND Applications >> Biochemical
BIND® is a label-free, highly flexible technology used for a variety of biochemical applications including protein-protein binding, small molecule and fragment-based screening, antibody characterization, multi-component binding assessment and enzyme assays.  BIND can identify stoichiometric binding compounds, rank affinity of target-ligand interactions and eliminate promiscuous binding compounds from a single sensitive measurement thereby pinpointing binders and eliminating problematic compounds from screening and profiling campaigns.   In addition, saturation binding of ligands and mechanisms of action can be evaluated in a highly parallel manner for increased efficiency in assay development, screening and lead characterization.
Biochemical Assay Features
  • Target Diversity
    • Proteins, peptides and fragments
    • Small molecules
    • Enzymes
    • Nucleic acids
  • Label-free
    • No binding interferences due to reagent labels
    • Multi-component, real time binding analysis
    • Simplified assay development and optimization
  • Throughput Flexibility: 16- to 1536-well assay format
  • Endpoint and Kinetic Measurements
General Biochemical Assays
>> Antibody Characterization
>> Identification of Aggregate &      Promiscuous Binders